f1 score (Oxford Instruments)
Structured Review

F1 Score, supplied by Oxford Instruments, used in various techniques. Bioz Stars score: 99/100, based on 41025 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/f1 score/product/Oxford Instruments
Average 99 stars, based on 41025 article reviews
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1) Product Images from "A deep learning pipeline for accurate and automated restoration, segmentation, and quantification of dendritic spines"
Article Title: A deep learning pipeline for accurate and automated restoration, segmentation, and quantification of dendritic spines
Journal: Cell Reports Methods
doi: 10.1016/j.crmeth.2025.101179
Figure Legend Snippet: Importance of image restoration in spine detection accuracy (A–C) Maximum intensity projection images of a dendritic segment acquired under low-SNR conditions (A), following CARE restoration (B), and at a high SNR (C). The right images in each row show RESPAN’s segmentation outputs, with color-coded spines denoting true positives (TPs; green), false positives (FPs; orange), or false negatives (FNs; magenta). Insets highlight spines that are barely distinguishable in the low-SNR dataset but can be resolved following restoration. (D) Detection rates (TPs, FPs, and FNs) for low-SNR (black) vs. restored (magenta) datasets. Statistical comparisons were performed using Wilcoxon matched-pairs signed-rank tests with a two-stage step-up method to control the false discovery rate. (E) Spine mask intersection-over-union (IoU = 0.5) analysis comparing segmentation labels from low-SNR and restored images to those from the high-SNR output. Each point represents a matched spine, and the line/whiskers depict the median and 95% confidence interval (CI); p values were obtained using Wilcoxon matched-pairs signed-rank tests. (F) F1 scores plotted across increasing IoU thresholds (0.1–0.9). Comparisons between low-SNR (black) and restored (magenta) curves were performed using Wilcoxon matched-pairs signed-rank tests. (G) Cumulative distributions of Hausdorff distances for low-SNR (black) and restored (magenta) spines, where lower values indicate closer alignment with the ground-truth spine shape. Data were analyzed by a Kolmogorov-Smirnov test, revealing significantly reduced Hausdorff distances in restored data.
Techniques Used: Control
Figure Legend Snippet: Comparison of RESPAN performance with other software (A) Maximum intensity projection of a raw fluorescence dataset showing a dendritic segment. (B–D) Spine detection outputs from RESPAN (B), DeepD3 (C), and Imaris (D) overlaying the dendritic segment. Detected spines are color coded as true positives (TPs; green), false positives (FPs; magenta), and false negatives (FNs; orange). (E) Percentage of TP spines detected by each method. (F) Recall scores for spine detection, with RESPAN demonstrating consistently higher recall, reflecting fewer FNs. (G) Precision scores for spine detection, with RESPAN outperforming DeepD3 and Imaris by reducing FP detections. (H) F1 scores for spine detection, representing the harmonic mean of precision and recall. RESPAN achieves superior F1 scores compared to other methods. (E)–(H) show a solid line at the median. Sample size: 440 GT spines from 11 dendritic segments.
Techniques Used: Comparison, Software, Fluorescence
